Spleen-colony Formation in Anemic Mice of Genotype Ww.

نویسندگان

  • E A MCCULLOCH
  • L SIMINOVITCH
  • J E TILL
چکیده

The hemopoietic cells from anemic mice of genotype WW are less able by 200-fold to take part in colony formationin the spleen than cells from the normal littermates of genotype ww. The genetic defect shows itself in the colony-forming cells, since cells from normal littermate mice formcolonies in the spleens of unirradiated mice of genotype WW. Use of animals of genotype WVVWT as recipients improves the spleen-colony method by removing bias resulting fromthe death of irradiated recipients.

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عنوان ژورنال:
  • Science

دوره 144 3620  شماره 

صفحات  -

تاریخ انتشار 1964